Try taking a look at the schematic for our retired Bus Pirate board. It has a PIC24FJ64 processor and a FT232RL integrated on the PCB and should give you a good general idea of how to have a PIC chip integrated with a FTDI chip:
The schematic should be self explanatory. There are also folks talking about interfacing a 16F628A (using INTOSC) via its serial port to an FTDI FT230XQ and having issues with speed: