I had a big-endian target (NET+ARM) which worked fine, but big-endian hosts are very rare, so I fear this is still untested. Basically it should work, I’ve reworked all endianess criticial parts in the code that I found.
When using a LPC23xx make sure you initally use a very low JTAG speed, as these uCs come out of reset running from a 4 MHz oscillator and the ARM7TDMI-S must not be run at more than 1/6th of that frequency. The FT2232 (IIRC you were using one?) runs at 6 MHz / (1 + jtag_speed), you should be fine with a value of 9 or 10.