Can't upload to my new arduino

I just built an arduino, I have made several before, but for some unknown reason I can’t get the FTDI Breakout board to communicate with the chip.

I have verified that both power pins have 5 volts,

the reset pin is connected to 5V via a 10K resister

The 6 pin header is connected as follows

DTR connected to reset via a 1 microF cap

Rx is connected to Tx on the chip

Tx is connected to Rx on the chip

5V is connected to 5V

Gnd is connected to Gnd

What happens is on the FTDI breakout board, rx flashes 3 times and then I get the message

avrdude: stk500_getsync(): not in sync: resp=0x00

If anyone has some idea how to see if the processor is working or not, or any thoughts I would be most appreciative.

What chip do you have?

Does it have a bootloader?

Right COM port?

Correct selection in the IDE?