The shield is setup so you can use either set of TX/RX pins. Pins #2,3 are the default. For Arduino boards this will require a soft serial port to be setup for pins 2,3 on the Arduino board. If you chose to use the RX/TX pins instead, you will need to remove the solder joint just above the RX/TX holes and form a new solder joint between the middle pad and the other (outer) pads. This will place the TX/RX lines on the TX/RX pins instead of pins 2,3.