The question here is not about which system of measure is better; the question is about which produces a shippable quality, cheaper to manufacture board.
Assuming you have parts in both Imperial (Inches & Mills; obvious case, headers & Through-Hole parts) and Metric units (Millimeters and Micrometers; obvious case, SMT parts), how do you draw the line between where you transition from Metric to Imperial, if anywhere, to produce a board that is as cheap as possible to manufacture?
An underlying assumption here is that, ideally, you want your board capable of being made on both Imperial and Metric equipment, and not limited to just one or the other, which presumably increases the competition available to produce your board. If it’s fundamentally cheaper to have a board made in one unit of measure than the other, that is worth noting, but please also remember to answer the original question in the assumed context; you never know when market conditions are going to change due to improved automation or increased labor costs.