I have been unable to get my 2021 MacBook Pro to recognize the CH340 chip using native Apple drivers or the most recent (2018) drivers (which I installed and then removed) available online. The card is not showing up in System Report/UUSB or in the Arduino IDE. Do I need to wait for newer OEM drivers? Thanks
Either that, or try changing to a known-good cable (can you test with another system/pc to verify the board/cable are functional?)