Cannot run basic motion: Motor driver

Just finished setting up the jetbot and tried to run the Basic_motion notebook but always get TimeoutError: [Errno 110] Connection timed out when i try to run: robot=Robot() on jupyter notebook.

Since I have already checked the cause in various ways, now I assume the problem is due to the motor driver. How can we finally identify the root cause?

Can you share a photo of how you have everything wired?